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| Product Name | Sp-Cyclic AMPS (sodium salt) |
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| Description | Purity >98%. Several cyclic nucleotide phosphodiesterases (PDE2, -5, -6, -10, and -11) contain a tandem of GAF domains in their N-terminal regulatory region that are thought to mediate cAMP- or cGMP-induced stimulation of adenylyl and guanylyl cyclases. Sp-cyclic AMPS (Sp-cAMPS) is a derivative of cAMP that binds the PDE10 GAF domain (EC50 = 40 µM). It has been used to study GAF-mediated stimulation of PDE10. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | cyclic 3',5'-[hydrogen (S)-phosphorothioate] adenosine, monosodium salt, Sp-cAMPS |
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| Gene, Accession, CAS # | CAS: 142439-95-0 |
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| Catalog # | LS-H9982 |
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| Order / More Info | Sp-Cyclic AMPS (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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