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| Product Name | CDC42, Recombinant Human |
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| Description | Purity ~95% by SDS-PAGE. Endotoxin: <1EU/ug (LAL). Cell division cycle 42 isoform 1, also known as CDC42, is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. Also, this protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Loss of CDC42 function caused an increase in the endocytotic uptake of apical proteins, including apical polarity factors such as Crumbs. Recombinant human CDC42, fused to T7-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human CDC42, aa1- 188, T7-tagged, expressed in E. coli AA Sequence: MASMTGGQQM GRGSHMQTIK CVVVGDGAVG KTCLLISYTT NKFPSEYVPT VFDNYAVTVM IGGEPYTLGL FDTAGQEDYD RLRPLSYPQT DVFLVCFSVV SPSSFENVKE KWVPEITHHC PKTPFLLVGT QIDLRDDPST |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001782 |
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| Catalog # | C2562-22 |
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| Order / More Info | CDC42, Recombinant Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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