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| Product Name | Fetuin A, Recombinant, Human |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Fetuin A/AHSG is a human plasma glycoprotein belonging to the Cystatin family of proteases inhibitors.It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages.Fetuin A/AHSG is a major serum protein component that exerts various calcium dependent physiological activities, and can mediate growth signaling in certain tumor cells. It also can act as a natural antagonist against specific TGF-beta and BMP signaling proteins, Recombinant human Fetuin-A is a heterodimeric protein containing a 282 amino acid A chain and a 27 amino acid B chain. Due to glycosylation, recombinant Fetuin-A migrates at an apparent molecular weight of 45-55kD by SDS-PAGE run under non-reducing conditions. Biological Activity: Determined by its ability to inhibit Cathespin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLUs). The expected IC50 is ~100nM. AA Sequence: A-Chain:APHGPGLIYR Q |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Fetuin A, Recombinant, Human (Alpha-2-HS-glycoprotein, Alpha-2-Z-globulin, Ba-alpha-2-glycoprotien) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143318 |
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| Order / More Info | Fetuin A, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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