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| Product Name | PD-L1, Recombinant, Human, aa19-239, FLAG-tag |
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| Description | Highly Purified (~90%). Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. Source: Recombinant protein corresponding to aa19-239 from human PD-L1, fused to FLAG-tag at C-terminal, expressed in HEK293 cell expression system. Molecular Weight: ~26kD, protein runs at a higher MW by SDS-PAGE due to glycosylation AA Sequence: FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQ HSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPY NKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFN VTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTDYKDDDDK Applications: Suitable for use in studying protein binding and for screening small molecules and antibodies. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PD-L1, Recombinant, Human, aa19-239, FLAG-tag (CD274, Programmed Cell Death 1 Ligand 1, CD274 and B7 Homolog 1, B7-H1, PDCD1 Ligand 1, Programmed Death Ligand 1, PDCD1L1) |
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| Gene, Accession, CAS # | Accession: NM_014143, SwissProt: Q9NZQ7 |
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| Catalog # | 298445 |
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| Order / More Info | PD-L1, Recombinant, Human, aa19-239, FLAG-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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