| 产品详情 |
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| Product Name | PD 153035 |
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| Description | Purity >98%. PD 153035 is a potent, reversible inhibitor of EGFR kinase (Ki = 5.2 pM; IC50 = 29 pM). It less effectively inhibits HER2 (IC50 = 2.3 µM) and has little effect on several other receptor and non-receptor tyrosine kinases. PD 153035 has been shown to rapidly suppress autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells, as well as to selectively block EGF-mediated cellular processes, including mitogenesis and early gene expression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(3-bromophenyl)-6,7-dimethoxy-4-quinazolinamine, SU 5271, AG-1517, NSC 669364 |
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| Gene, Accession, CAS # | CAS: 153436-54-5 |
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| Catalog # | LS-H9289 |
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| Price | |
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| Order / More Info | PD 153035 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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