| 产品详情 |
| Edit |   |
|---|
| Product Name | PD 158780 |
|---|
| Description | Purity >98%. PD 158780 is a pyridopyrimidine derivative that reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor tyrosine kinase superfamily: EGFR (IC50 = 8 µM), ErbB2 (IC50 = 49 nM), ErbB3, and ErbB4 (IC50 = 52 nM). It does not inhibit PDGF or FGF-mediated tyrosine phosphorylation. At 0.5 µM, PD 158780 has been shown to induce G1 cell cycle arrest in MCF10A breast cancer cells. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N4 -(3-bromophenyl)-N6 -methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
|---|
| Gene, Accession, CAS # | CAS: 171179-06-9 |
|---|
| Catalog # | LS-H9293 |
|---|
| Price | |
|---|
| Order / More Info | PD 158780 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|