| 产品详情 |
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| Antigenic Specificity | CD279 (PD-1) |
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| Clone | EH12.2H7 |
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| Host Species | Mouse |
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| Reactive Species | chimpanzee, cynomolgus monkey, human, nonhuman primate, rhesus monkey |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD279 (PD-1) Monoclonal Antibody (EH12.2H7). CD279/PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its receptors CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their energy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 100135775, 100400173, 101044440, 102123659, 5133, 748796; Uniprot: Q15116 |
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| Catalog # | MA5-28584 |
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| Price | |
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| Order / More Info | CD279 (PD-1) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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