| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | BU63 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg x 10^6 cells in 100 µL, Functional Assay: Assay Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 Monoclonal Antibody (BU63). CD86 is one of two ligands (the other CD80) for CTLA4 and CD28. CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation. Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD80 appears to play a role distinct from CD80 in T helper cell differentiation. CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily. The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding |
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| Immunogen | n/a |
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| Other Names | B7-2, B7.2, B70, CD28LG2, LAB72, MGC34413, B-lymphocyte activation antigen B7-2, B-lymphocyte antigen B7-2, B7-2 antigen, BU63, CD28 antigen ligand 2 |
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| Gene, Accession # | Entrez: 942; Uniprot: P42081 |
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| Catalog # | MA1-10293 |
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| Price | |
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| Order / More Info | CD86 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11781389, 11907076, 12117904, 12646628, 12830324, 15271069, 15356117, 15528334, 15720437, 15725957, 15743001, 15902686, 15943619, 15961579, 15972685, 16175399, 16830104, 16859998, 17034427, 17132718, 18512812, 18981105, 19479861, 19734213, 21504576, 21993649, 22321156, 22386694, 22479639, 24341794, 28341289 |
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