| 产品详情 |
| Edit |   |
|---|
| Product Name | SKF-96365 |
|---|
| Description | Purity >98% by NMR, TLC. SKF-96365 is an inhibitor of receptor-mediated calcium entry (RMCE) with IC50's of 8.5 uM for ADP stimulated platelets and 11.7 uM for thrombin stimulated platelets. Also inhibits Voltage-gated Ca2+ but not ATP-gated Ca2+ entry. It has also been shown to block transient receptor potential canonical type (TRPC) channels, high-voltage-activated (HVA) L-type channels1, K channels, sarcoplasmic reticulum Ca-ATPase and voltage-gated sodium channels. SKF-96365 is a potent blocker of LVA T-type Ca channels, in particular Ca(V)3.1 (IC50 = 0.56 uM). |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1-[2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]imidazole hydrochloride |
|---|
| Gene, Accession, CAS # | CAS: 130495-35-1 |
|---|
| Catalog # | LS-H14844 |
|---|
| Price | |
|---|
| Order / More Info | SKF-96365 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|