| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Osteopontin |
|---|
| Clone | 2F10 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: Assay-Dependent |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Osteopontin Monoclonal Antibody (2F10), eBioscience™. Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D. |
|---|
| Immunogen | n/a |
|---|
| Other Names | 44 kDa bone phosphoprotein; BNSP; bone sialoprotein 1; calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; minopontin; nephropontin; OPN; osteopontin; osteopontin-like protein; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; PSEC0156; Secreted Phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; SPP-1; SPP1/CALPHA1 fusion; urinary stone protein; uropontin |
|---|
| Gene, Accession # | Entrez: 6696; Uniprot: P10451 |
|---|
| Catalog # | 14-9096-82 |
|---|
| Price | |
|---|
| Order / More Info | Osteopontin Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|