| 产品详情 |
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| Antigenic Specificity | Osteopontin |
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| Clone | 2F10 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | eFluor 660 conjugate |
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| Size | 25 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Osteopontin Monoclonal Antibody (2F10), eFluor 660, eBioscience™. Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D. |
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| Immunogen | n/a |
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| Other Names | 44 kDa bone phosphoprotein; BNSP; bone sialoprotein 1; calcium oxalate crystal growth inhibitor protein; early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; minopontin; nephropontin; OPN; osteopontin; osteopontin-like protein; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; PSEC0156; Secreted Phosphoprotein 1; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; SPP-1; SPP1/CALPHA1 fusion; urinary stone protein; uropontin |
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| Gene, Accession # | Entrez: 6696; Uniprot: P10451 |
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| Catalog # | 50-9096-41 |
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| Price | |
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| Order / More Info | Osteopontin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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