产品详情 |
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Antigenic Specificity | GLI2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50, Western Blot: 1-8 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GLI2 Polyclonal Antibody. This protein belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly typ |
Immunogen | n/a |
Other Names | GLI family Zinc finger 2, HPE9, THP1, THP2 |
Gene, Accession # | Entrez: 2736; Uniprot: P10070 |
Catalog # | PA5-40443 |
Price | |
Order / More Info | GLI2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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