| 产品详情 |
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| Antigenic Specificity | SHMT2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SHMT2 Polyclonal Antibody. Mammalian serine hydroxymethyltransferase (SHMT) is a tetrameric, pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible interconversion of serine and tetrahydrofolate to glycine and methylenetetrahydrofolate in the cytoplasm (cSHMT, SHMT1) and mitochondria (mSHMT, SHMT2). cSHMT preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate, and inhibits SAM synthesis. |
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| Immunogen | n/a |
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| Other Names | GLYA, SHMT, GLY A+, glycine auxotroph A, human complement for hamster, glycine hydroxymethyltransferase, serine aldolase, serine hydroxymethylase, serine hydroxymethyltransferase, mitochondrial, serine methylase, threonine aldolase |
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| Gene, Accession # | Entrez: 108037, 299857, 6472; Uniprot: P34897 |
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| Catalog # | PA5-54232 |
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| Price | |
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| Order / More Info | SHMT2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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