| 产品详情 |
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| Antigenic Specificity | GLRA1 |
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| Clone | 4D6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GLRA1 Monoclonal Antibody (4D6). GLRA1 is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in GLRA1 are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found for GLRA1. Glycine receptors (GlyR) that include GLRA1 are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine. GLRA1 are widely distributed throughout the CNS, particularly within the hippocampus, spinal cord and brain stem. Diseases associated with GLRA1 include Hyperekplexia, Hereditary 1 and Hyperekplexi |
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| Immunogen | n/a |
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| Other Names | GLRA1, Glra2, GLYRA1, Glycine receptor subunit alpha-1, Glycine receptor subunit alpha-2 |
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| Gene, Accession # | Entrez: 2741; Uniprot: P23415 |
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| Catalog # | MA5-18977 |
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| Price | |
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| Order / More Info | GLRA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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