产品详情 |
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Antigenic Specificity | Thioredoxin 1 |
Clone | 8A1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2 µg |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Thioredoxin 1 Monoclonal Antibody (8A1). Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cystein residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide |
Immunogen | n/a |
Other Names | ADF, ATL-derived factor, SASP |
Gene, Accession # | Entrez: 7295; Uniprot: P10599 |
Catalog # | LF-MA0077 |
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Order / More Info | Thioredoxin 1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 21963381 |
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