| 产品详情 |
| Edit |   |
|---|
| Product Name | SJ 172550 |
|---|
| Description | Purity >98%. SJ 172550 is an inhibitor of MDMX that disrupts MDMX-p53 peptide interaction with an EC50 value of 4.3 µM. It forms a covalent, but reversible, cysteine adduct in the MDMX p53-binding domain, locking MDMX into a conformation that prevents binding to p53. SJ 172550 induces apoptosis, increases p53 target gene expression, and causes p53-dependent cell death in retinoblastoma cells. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[2-chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-acetic acid, methyl ester, MDMX Inhibitor II |
|---|
| Gene, Accession, CAS # | CAS: 431979-47-4 |
|---|
| Catalog # | LS-H9938 |
|---|
| Price | |
|---|
| Order / More Info | SJ 172550 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|