| 产品详情 |
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| Product Name | PI-103, Free Base |
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| Description | PI-103 is acts as a dual inhibitor of class IA phosphatidylinositide 3-kinase (PI3K) and mTOR. PIP3 activates Akt and mTOR, and plays important roles in cell growth and survival. PI-103 was mainly cytostatic for human leukemic cell lines and induced cell cycle arrest in the G1 phase. PI-103 inhibited endothelial cell proliferation and survival in vitro and tumor growth in vivo possibly by blocking activation of both PI3K and mTOR in vGPCR-expressing endothelial cells. PI-103 has been seen to have nominal effects inhibiting basal Na+ transport, but is very effective in abolishing insulin-induced Na+ absorption in the nephron. MW: 348.36 g/mol. Purity >99% pure |
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| Size | 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 250 mg, 500 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PI103, PI 103 |
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| Gene, Accession, CAS # | CAS: 371935-74-9 |
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| Catalog # | orb153627 |
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| Order / More Info | PI-103, Free Base from BIORBYT LTD. |
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| Product Specific References | n/a |
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| 产品资料 |
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