产品详情 |
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Product Name | HA-155 |
Description | Purity >95%. Autotaxin converts lysophosphatidylcholine to lysophosphatidic acid (LPA), which can mediate changes in cell proliferation, angiogenesis, and cytokine secretion. HA-155 is a boronic acid-based compound that inhibits autotaxin (IC50 = 5.7 nM) by selectively binding to its catalytic threonine. It has been shown to dose-dependently block thrombin-induced LPA secretion in platelets. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | B-[4-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid, Autotaxin Inhibitor IV |
Gene, Accession, CAS # | CAS: 1229652-22-5 |
Catalog # | LS-H8070 |
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Order / More Info | HA-155 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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