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| Product Name | BPNT1, Recombinant, Human, aa1-308, His-tag |
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| Description | Purity ~90% (SDS-PAGE). BPNT1, also known as BPntase, PAP phosphatase or PIP (PAP-inositol-1,4-phosphatase), is a member of the magnesium-dependent, lithium-sensitive phosphomono-esterase superfamily. Using magnesium as a cofactor, BPNT1 catalyzes the conversion of PAPS (adenosine 3'-phosphate 5' phosphosulfate) to APS (adenosine 5'-phosphosulfate) and the conversion of PAP (3'(2')-phosphoadenosine 5' phosphate) to AMP (adenosine 5'-phosphate). Expressed ubiquitously with highest levels in brain and kidney, BPNT1 is potently inhibited by lithium, a drug used for the treatment of manic depression and bipolar affective disorder, suggesting a possible role for BPNT1 in the etiology of mood disorders. Source: Recombinant protein corresponding to aa1-308 from human BPNT1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~37.5kD (344aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BPNT1, Recombinant, Human, aa1-308, His-Tag (3'(2'), 5'-bisphosphate nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase) |
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| Gene, Accession, CAS # | Accession: NP_006076 |
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| Catalog # | 351108 |
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| Order / More Info | BPNT1, Recombinant, Human, aa1-308, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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