产品详情 |
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Antigenic Specificity | GSK3 Alpha Ser21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GSK3 Alpha(Ser21) Polyclonal Antibody. • Target Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Re |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha around the phosphorylation site of Ser21. Immunogen Range: 1-50/483 |
Other Names | Phosphorylated, phospho-Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3A |
Gene, Accession # | Gene ID: 2931, SwissProt: P49840 |
Catalog # | bs-4692R |
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Order / More Info | GSK3 Alpha Ser21 Antibody from BIOSS ANTIBODIES |
Product Specific References | Zhang, Weidong, et al. (2017) Chemosphere. PubMed: 29202267 |
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