产品详情 |
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Antigenic Specificity | Cyclophilin 40 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | canine, hamster, human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclophilin 40 Polyclonal Antibody. Cyclophilin D (CyPD) is a member of the immunophilin family of proteins. Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP). Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins. CyPD is located |
Immunogen | n/a |
Other Names | Cyp D, Peptidyl-prolyl cis-trans isomerase D, EC 5.2.1.8, PPIase, Rotamase, S-cyclophilin, SCYLP, CYP-S1 |
Gene, Accession # | Entrez: 100752921, 361967, 475481, 5481, 67738; Uniprot: Q08752, Q6DGG0, Q9CR16 |
Catalog # | PA1-028 |
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Order / More Info | Cyclophilin 40 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15229226, 15792954, 16331251, 16675492, 18638546, 19244535, 19966057, 20543078, 21121808, 26082307, 26497962 |
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