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| Product Name | Rat FGF18 Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE and HPLC, MW: 20.1 kDa (SDS-PAGE). Fibroblast Growth Factor 18 (FGF-18) is a pleiotropic cytokine belonging to the heparin-binding FGF family, which has 23 different members. Structurally, FGF-18 is closely related to FGF-8 and FGF-17. Like other FGFs, FGF-18 can bind to different FGF receptors in vivo. FGF-18 is expressed in various tissues and has multiple functions: during long bone growth, FGF-18 is expressed in perichondrium and developing joints, and regulates bone formation by inhibiting chondrocyte proliferation and differentiation; FGF-18 knock-out mice survive embryonic development, but exhibit skeletal abnormalities and die in the early neonatal period. FGF-18 also induces ectopic cartilage formation in the lung, and alters the morphology of the pulmonary mesenchyma. Recombinant rat Fibroblast Growth Factor 18 (rrFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing of 172 amino acids. A fully biologically active molecule, rrFGF-18 has a molecular mass of 20.1 kDa analyzed by non-reducing SDS-PAGE and is obtained by chromatographic techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FGF18, FGF-18, ZFGF5, Fibroblast growth factor 18 |
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| Gene, Accession, CAS # | FGF18, Gene ID: 8817 |
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| Catalog # | LS-G27174 |
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| Order / More Info | Rat FGF18 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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