| 产品详情 |
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| Antigenic Specificity | Metadherin |
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| Clone | 21H9L18 |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-3 µg/mL, Immunofluorescence: 1:100-1:500, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1-3 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Metadherin Antibody (21H9L18), ABfinity™ Rabbit Monoclonal. Metadherin (MTDH) was originally identified as an oncogene, and plays a role in promoting proliferation, invasion, survival, and enhancing chemoresistance. Expression of MTDH is associated with Ha-ras, PI3K/Akt, NF- kappaB and Wnt/ beta-catenin signaling pathways. Immunoflurescence and histochemical analysis has shown perinuclear, nucleolar, and cytoplasmic staining, while upregulated MTDH expression has been shown to enhance nuclear localization. The protein has three putative lysine-rich nuclear localization signals and this antibody has been raised specifically against the NLS3 region. |
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| Immunogen | n/a |
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| Other Names | 3D3, AEG1, AEG-1, LYRIC, LYRIC/3D3, MTDH |
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| Gene, Accession # | Entrez: 67154, 92140; Uniprot: Q80WJ7, Q86UE4 |
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| Catalog # | 701171 |
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| Price | |
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| Order / More Info | Metadherin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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