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Product Name | Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (Active) protein |
Description | OX40L, a member of the TNF superfamily of structurally related proteins, exists primarily as a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells (APCs), such as dendritic cells and activated B-cells, and also on various other cells such as vascular endothelial cells, mast cells, and natural killer cells. OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL2, IL3, and IFN. Alternative Names: OX40 Ligand, OX40L protein, OX Ligand-40, CD252 protein, OX Ligand-40 protein, OX Ligand 40 protein, Gp34 protein, TNFSF4 protein, OX Ligand 40 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | TNFSF4|OX40L|TNFRSF4|CD134L|CD252|GP34|OX-40L|OX4OL|TXGP1|Ath-1|Ath1|Ox40l|Txgp1l|gp34 |
Gene, Accession, CAS # | Gene ID: 7292 |
Catalog # | ABIN935701 |
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Order / More Info | Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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