| 产品详情 |
| Edit |   |
|---|
| Product Name | Cyclothiazide |
|---|
| Description | Purity >95%. Receptors for AMPA are ionotropic glutamate receptors with critical roles in neurological development and function. Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 µM). It blocks the rapid agonist-induced desensitization of AMPA receptors, resulting in enhanced excitatory activity. Cyclothiazide is also a negative modulator of GABAA receptors, reversibly inhibiting both evoked and spontaneous inhibitory postsynaptic currents (IC50 = 58 µM). |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 1,1-dioxide 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, Doburil |
|---|
| Gene, Accession, CAS # | CAS: 2259-96-3 |
|---|
| Catalog # | LS-H7306 |
|---|
| Price | |
|---|
| Order / More Info | Cyclothiazide from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|