| 产品详情 |
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| Antigenic Specificity | Phospho-ITGB1 (Thr788, Thr789) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Western Blot: 1:250 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-ITGB1 (Thr788, Thr789) Polyclonal Antibody. CD29 (beta1 integrin subunit, GPIIa) forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CD49a-f) determining the binding properties of beta1 (VLA) integrins. These integrins mediate cell adhesion to collagen, fibronectin, laminin and other extracellular matrix (ECM) components. This interaction hinders cell death, whereas disruption of anchorage to ECM leads to apoptosis. Decreased expression of most beta1 integrins correlates with acquiring multidrug resistance of tumour cells during selection in presence of antitumour drug. In platelets, translocation of intracellular pool of beta1 integrins to the plasma membrane following thrombin stimulatio |
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| Immunogen | n/a |
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| Other Names | CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, ITGB1 |
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| Gene, Accession # | Entrez: 3688; Uniprot: P05556 |
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| Catalog # | 44-872G |
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| Order / More Info | Phospho-ITGB1 (Thr788, Thr789) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12788385, 15494436 |
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