产品详情 |
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Antigenic Specificity | CD4 |
Clone | RM4-5 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Qdot 605 conjugate |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD4 Monoclonal Antibody (RM4-5), Qdot 605. The CD4 antigen is expressed on the majority of normal thymocytes and on the MHC class II restricted subset of mature T cells, including T helper cells, and is involved in the recognition of the type II MHC antigen. As a co-receptor in the TCR complex, CD4 is involved in T cell activation through interaction with MHC class II on antigen presenting cells and in signal transduction via the cytoplasmic portion of CD4 through protein tyrosine kinase p56lck. It is also a receptor for HIV. CD4 expression is commonly found in human lymph nodes and tonsils. Mouse CD4 antigen has been reported to be present on multipotential hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic precursor |
Immunogen | n/a |
Other Names | CD4 antigen p55, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
Gene, Accession # | Entrez: 12504; Uniprot: P06332 |
Catalog # | Q10092 |
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Order / More Info | CD4 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 22629361, 22676339, 23544080, 24908390, 26010544 |
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