| 产品详情 |
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| Antigenic Specificity | CD49e |
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| Clone | P1D6 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG3 |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-CD49e (Integrin α5). CD49e is a type I integral membrane glycoprotein, known as α5 integrin, or VLA-5 α chain. It forms noncovalent heterodimer with integrin β1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronectin and neural adhesion molecule L1. It mediates monocytes migration, it is involved in the regulation of cells survival and apoptosis, and co-stimulates T cell activation. |
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| Immunogen | The P1D6 monoclonal antibody was generated against human HT1080 fibrosarcoma cells and reacts with the α5 integrin subunit. |
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| Other Names | FNRA, VLA5A, Integrin alpha-5, VLA-5, integrin alpha-F, CD49 antigen-like family member E, fibronectin receptor subunit alpha, very late activation protein 5, alpha subunit |
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| Gene, Accession # | Gene ID: 3678 |
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| Catalog # | 921704 |
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| Price | |
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| Order / More Info | CD49e Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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