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Antigenic Specificity | VCAM-1 |
Clone | 1.4C3 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:10-1:100, Immunofluorescence: 1:10-1:100, Immunohistochemistry (Frozen): 1:12.5-1:25, Immunohistochemistry (Paraffin): 1:12.5-1:25 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VCAM-1 Monoclonal Antibody (1.4C3). CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-110) is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on unstimulated endothelial cells. It is also present on follicular and interfollicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin alphaBeta (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in tumor metastasis. |
Immunogen | n/a |
Other Names | CD106, DKFZp779G2333, INCAM-100, MGC99561, CD106 antigen, vascular cell adhesion protein 1 |
Gene, Accession # | Entrez: 22329, 7412; Uniprot: P19320, P29533 |
Catalog # | MA5-11447 |
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Order / More Info | VCAM-1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16321827, 19228707, 21040770, 22551965, 29187895 |
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