| 产品详情 |
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| Antigenic Specificity | ITGA4 |
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| Clone | PS/2 |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:50-1:100, Functional Assay: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Immunoprecipitation: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITGA4 Monoclonal Antibody (PS/2). CD49d, also known as integrin alpha-4 or VLA-4 subunit alpha, is a ~150kDa single pass type 1 transmembrane glycoprotein that contains seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa. CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria. |
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| Immunogen | n/a |
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| Other Names | 269C wild type, CD49 antigen-like family member D, VLA-4 subunit alpha, antigen CD49D, alpha-4 subunit of VLA-4 receptor, ITGA4, ITGA-IV |
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| Gene, Accession # | Entrez: 16401, 3676; Uniprot: P13612, Q00651 |
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| Catalog # | MA1-82769 |
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| Price | |
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| Order / More Info | ITGA4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 9378760 |
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