| 产品详情 |
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| Product Name | 4,5,6,7-Tetrabromobenzimidazole |
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| Description | Purity >98%. Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors. 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2 with Ki values ranging from 0.5-1 µM in rat liver, S. cerevisiae, C. tropicalis, and N. crassa . It is inactive against PKA and PKC and a relatively weak inhibitor of CK1 (Ki = 54.4-64.2 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4,5,6,7-tetrabromo-1H-benzimidazole, Casein Kinase II Inhibitor XII, TBBz |
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| Gene, Accession, CAS # | CAS: 577779-57-8 |
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| Catalog # | LS-H6093 |
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| Order / More Info | 4,5,6,7-Tetrabromobenzimidazole from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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