产品详情 |
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Antigenic Specificity | ULK3 |
Clone | 4C5 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 κ |
Format | purified |
Size | 100ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ULK3 (4C5) Monoclonal Antibody. • Target Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nucl |
Immunogen | This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3. |
Other Names | Serine/threonine-protein kinase ULK3; Unc-51-like kinase 3; ULK3 |
Gene, Accession # | Gene ID: 25989, SwissProt: Q6PHR2 |
Catalog # | bsm-51408M |
Price | |
Order / More Info | ULK3 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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