| 产品详情 |
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| Product Name | Bizine |
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| Description | Purity >95%. Bizine is a phenelzine analog that inhibits lysine-specific demethylase 1 (LSD1; Ki(inact) = 59 nM). It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Bizine has been shown to induce bulk histone H3 lysine 4 dimethylation in LNCaP cancer cells (EC50 = ~2 µM) and, at 0.5 µM, to protect neurons exposed to oxidative stress. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-(2-hydrazinylethyl)phenyl]-benzenebutanamide |
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| Gene, Accession, CAS # | CAS: 1591932-50-1 |
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| Catalog # | LS-H6839 |
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| Order / More Info | Bizine from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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