产品名称 HMB-Val-Ser-Leu-VE from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H8113
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameHMB-Val-Ser-Leu-VE
DescriptionPurity >98%. The 20S proteasome is a 700 kDa, multi-subunit cylinder-shaped protein that functions as the central protease within the ubiquitin-proteasome pathway utilized by cells for the regulated degradation of proteins. HMB-val-ser-leu-VE is a tripeptide bearing a C-terminal vinyl ester which acts as a potent, selective inhibitor of the trypsin-like activity of the 20S proteasome. It inhibits the tryptic-like, chymotryptic-like, and post acidic activities of the purified 20S proteasome with IC50 values of 0.33 µM, >10 µM, and >10 µM, respectively. HMB-val-ser-leu-VE is cell permeable and stable (t1/2 ~6 hours) in in vitro assays.
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Other NamesN-(3-hydroxy-2-methylbenzoyl)-L-valyl-N-[(1S,2E)-4-ethoxy-1-(2-methylpropyl)-4-oxo-2-butenyl]-L-serinamide
Gene, Accession, CAS #CAS: 862891-04-1
Catalog #LS-H8113
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Order / More InfoHMB-Val-Ser-Leu-VE from LIFESPAN BIOSCIENCES INC.
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