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| Product Name | 25(R)-27-hydroxy Cholesterol |
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| Description | Purity >95%. The liver x receptors (LXRAlpha and LXRBeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRAlpha and LXRBeta in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. 25(R)-27-hydroxy Cholesterol is the more predominant-occurring (~80%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (25R)-cholest-5-ene-3Beta,26-diol, (25R)-26-hydroxy cholesterol |
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| Gene, Accession, CAS # | CAS: 20380-11-4 |
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| Catalog # | LS-H5956 |
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| Order / More Info | 25(R)-27-hydroxy Cholesterol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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