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| Product Name | Human TS / Thymidylate Synthase Protein (Recombinant His tag) |
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| Description | Purity >95% by SDS-PAGE. Thymidylate synthase is an intracellular enzyme critical for de novo synthesis of DNA. This function maintains the dTMP(thymidine-5-prime monophosphate) pool critical for DNA replication and repair. In cancer, expression of this protein is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-Fu). Resistance or lack of response to 5-Fu is attributed to the elevation of thymidylate synthase activity. Recombinant human Thymidylate synthase protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TYMS, HST422, Thymidylate synthetase, TMS, TS, Thymidylate synthase, Tsase |
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| Gene, Accession, CAS # | TYMS, Gene ID: 7298 |
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| Catalog # | LS-G667 |
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| Order / More Info | Human TS / Thymidylate Synthase Protein (Recombinant His tag) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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