| 产品详情 |
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| Antigenic Specificity | Phospho-HDAC7 (Ser448) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | bovine, canine, equine, human, nonhuman primate, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Western Blot: 0.1-0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-HDAC7 (Ser448) Polyclonal Antibody. Histone deacetylase 7 is a thymus-specific, intracellular transcription factor belonging to the class IIa histone deacetylase family. Reports suggest that dephosphorylation and nuclear localization of HDAC-7 is promoted by Myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+CD8+ double-positive thymocytes. HDAC-7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the |
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| Immunogen | n/a |
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| Other Names | HD7A, HDAC7A, HD7, histone deacetylase 7A |
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| Gene, Accession # | Entrez: 100050617, 486589, 509843, 51564, 84582; Uniprot: Q8WUI4, Q99P96 |
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| Catalog # | PA5-23384 |
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| Price | |
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| Order / More Info | Phospho-HDAC7 (Ser448) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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