产品详情 |
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Antigenic Specificity | Parkin |
Clone | PRK109 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, kappa |
Format | purified |
Size | 1 mL |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Immunofluorescence: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Parkin Monoclonal Antibody (PRK109). Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. |
Immunogen | n/a |
Other Names | AR-JP, LPRS2, PDJ, PRKN, E3 ubiquitin-protein ligase parkin, Parkinson disease autosomal recessive, juvenile 2, parkin, parkinson juvenile disease protein 2 |
Gene, Accession # | Entrez: 5071, 50873, 56816; Uniprot: O60260, Q9JK66, Q9WVS6 |
Catalog # | 39-0900 |
Price | |
Order / More Info | Parkin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12972409 |
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