| 产品详情 |
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| Product Name | CPI-613 |
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| Description | Purity >98%. Lipoic acid is a natural organosulfur compound that serves as a cofactor in various complexes, including the Alpha-ketoglutarate dehydrogenase complex, which is involved in the citric acid cycle as well as other pathways. CPI-613 is a lipoic acid analog that inhibits Alpha-ketoglutarate dehydrogenase, particularly in tumor cells. At 60-240 µM, CPI-613 induces a strong mitochondrial burst of reactive oxygen species, resulting in cell death. By disrupting mitochondrial metabolism, CPI-613 demonstrates both in vitro and in vivo anti-tumor activity through both apoptotic and non-apoptotic pathways. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6,8-bis[(phenylmethyl)thio]-octanoic acid |
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| Gene, Accession, CAS # | CAS: 95809-78-2 |
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| Catalog # | LS-H7257 |
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| Price | |
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| Order / More Info | CPI-613 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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