产品详情 |
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Product Name | Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8) peptide |
Description | The C17ORF71 protein is a component of the SMG1C complex, a mRNA surveillance complex that recognises and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD). |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | C19H17orf71|1200011M11Rik|C17orf71 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN939088 |
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Order / More Info | Smg-8 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans) (SMG8) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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