产品详情 |
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Antigenic Specificity | Adiponectin |
Clone | 19F1 |
Host Species | Mouse |
Reactive Species | human, mouse, rabbit |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay dependent, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2-4 µg/mL, Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Adiponectin Monoclonal Antibody (19F1). Adiponectin is a protein hormone secreted exclusively by adipocytes that regulates the metabolism of lipids and glucose. Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve insulin signaling, thus ameliorating insulin resistance. Through activation of AMP kinase and PPAR-alpha, adiponectin can increase fatty acid transport, oxidation, and dissipation in skeletal muscle, leading to a reduction of intramyocellular lipid levels and thus improved insulin signaling |
Immunogen | n/a |
Other Names | Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, ACRP30, Adipose most abundant gene transcript 1, a |
Gene, Accession # | Entrez: 100009027, 11450, 9370; Uniprot: Q15848, Q60994 |
Catalog # | MA1-054 |
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Order / More Info | Adiponectin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 20516556, 22595290, 22623686, 23186800, 23250756, 23983791, 25136373, 26274372, 26696121 |
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