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| Product Name | Recombinant Human Alpha-endosulfine (ENSA) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 40.4kDa. Full Length: 1-121aa. N-terminal GST-tagged. Homo sapiens (Human). Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K (ATP) channel currents.1 Publication |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | ARPP-19e |
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| Gene, Accession, CAS # | ENSA, UniProt: O43768 |
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| Catalog # | RPC23976 |
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| Order / More Info | Recombinant Human Alpha-endosulfine (ENSA) from BIOMATIK |
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| Product Specific References | n/a |
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