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| Product Name | IFI30, Recombinant, Human, aa58-232, His-tag |
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| Description | Purity ~90% (SDS-PAGE). IFI30, also as known as gamma-interferon-inducible lysosomal thiol reductase, belongs to the GILT family. This protein is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing. This protein facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds. Also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation Source: Recombinant protein corresponding to aa58-232 from human IFI30, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~22.5kD (199aa) AA |
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| Size | 50ug, 250ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IFI30, Recombinant, Human, aa58-232, His-Tag (Gamma-interferon-inducible lysosomal thiol reductase, GILT, IFI-30, IP30) |
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| Gene, Accession, CAS # | Accession: NP_006323 |
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| Catalog # | 351297 |
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| Order / More Info | IFI30, Recombinant, Human, aa58-232, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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