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| Product Name | Recombinant Human metapneumovirus Matrix protein (M) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 35.1kDa. Full Length: 1-254aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Human metapneumovirus (strain CAN97-83) (HMPV). Has a crucial role in virus assembly and budding. The matrix interacts with the RNP complex and this association serves two functions: facilitate virion assembly and inhibit the viral transcriptase activity. Early in infection, M is localized to the nucleus and may inhibit host cell transcription. Later on, M can associate with lipid rafts supposely by interacting with the cytoskeleton and with the cytoplasmic tail of glycoprotein G. The binding of M to host membrane is stabilized by the surface expression of the viral glycoproteins. These interactions may allow virus formation by mediating association of the nucleocapsid with the nascent envelope. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | M, UniProt: Q6WB99 |
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| Catalog # | RPC25822 |
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| Order / More Info | Recombinant Human metapneumovirus Matrix protein (M) from BIOMATIK |
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| Product Specific References | n/a |
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