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Antigenic Specificity | AIF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, porcine |
Isotype | n/a |
Format | Alexa Fluor® 594 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AIF Polyclonal Antibody, Alexa Fluor® 594 Conjugated. • Target Background: Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of ch |
Immunogen | KLH conjugated synthetic peptide derived from human AIF. Immunogen Range: 130-180/613 |
Other Names | AIF; CMT2D; CMTX4; COWCK; NADMR; NAMSD; PDCD8; COXPD6; Apoptosis-inducing factor 1, mitochondrial; Programmed cell death protein 8; AIFM1 |
Gene, Accession # | Gene ID: 9131, SwissProt: O95831 |
Catalog # | bs-0037R-A594 |
Price | |
Order / More Info | AIF Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |