| 产品详情 |
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| Antigenic Specificity | AIF |
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| Clone | 4E7E11 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, nonhuman primate, rat |
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| Isotype | IgG2b |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:100, Immunofluorescence: 1:50-1:100, Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AIF Monoclonal Antibody (4E7E11). Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation. AIF was recently identified, and cloned. Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the |
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| Immunogen | n/a |
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| Other Names | RP3-438D16.2, AIF, COXPD6, PDCD8, apoptosis-inducing factor 1, mitochondrial; programmed cell death 8 (apoptosis-inducing factor); striatal apoptosis-inducing factor |
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| Gene, Accession # | Entrez: 26926, 83533, 9131; Uniprot: O95831, Q9JM53, Q9Z0X1 |
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| Catalog # | MA5-15880 |
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| Price | |
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| Order / More Info | AIF Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 25583628, 26915330 |
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