| 产品详情 |
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| Antigenic Specificity | LPIN1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 5 µg/mL, Western Blot: 1-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LPIN1 Polyclonal Antibody. LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria and it is also a candidate for several human lipodystrophy syndromes. |
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| Immunogen | n/a |
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| Other Names | LPIN1, PAP1, Lipin 1, fatty liver dystrophy protein, phosphatidate phosphatase LPIN1 |
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| Gene, Accession # | Entrez: 14245, 23175, 313977; Uniprot: Q14693, Q91ZP3 |
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| Catalog # | PA5-34566 |
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| Price | |
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| Order / More Info | LPIN1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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