产品详情 |
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Antigenic Specificity | LPHN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 50 ug |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 8 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LPHN1 Polyclonal Antibody. Adgrl1 (Latrophilin-1) is a calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Adgrl1 is a receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization, and may be implicated in the regulation of exocytosis. The Adgrl1 gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) do |
Immunogen | n/a |
Other Names | LPHN1, Alpha-latrotoxin receptor, CIRL-1, CIRL1, Cl1 latrotoxin receptor, Latrophilin 1, Latrophilin-1, Lphh2, KIAA0821, LEC2, Cirl, CL1, Lectomedin-2 |
Gene, Accession # | Entrez: 22859; Uniprot: O94910 |
Catalog # | PA5-33903 |
Price | |
Order / More Info | LPHN1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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