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| Product Name | BRD4 (BD1+BD2), Recombinant, Human, aa49-460, GST-tag (Bromodomain Containing 4, HUNK1, MCAP) |
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| Description | Purified (~80%). The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]. Source: Recombinant protein corresponding to aa49-460 from human Bromodomain containing 4, fused to GST-tag at N-terminal, expressed in E. coli. Molecular Weight: ~73.3kD Applications: Suitable for use in the study of bromodomain binding assays, screening inhibitors, and selectivity profiling. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_058243, SwissProt: O60885 |
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| Catalog # | 298362 |
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| Order / More Info | BRD4 (BD1+BD2), Recombinant, Human, aa49-460, GST-tag (Bromodomain Containing 4, HUNK1, MCAP) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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