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Antigenic Specificity | GRAF |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunohistochemistry: 3.75 µg/mL, peptide-ELISA: 1:64000, Western Blot: 0.3-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GRAF Polyclonal Antibody. Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia . Two transcript variants encoding different isoforms have been found for this gene. |
Immunogen | n/a |
Other Names | ARHGAP26; GRAF; Rho GTPase activating protein 26 ; KIAA0621; FLJ42530; OPHN1L; OPHN1L1; GTPase regulator associated with FAK; GTPase regulator associated with focal adhesion kinase pp125(FAK); GTPase regulator associated with the focal adhesion kinase pp125 |
Gene, Accession # | Entrez: 23092; Uniprot: Q9UNA1 |
Catalog # | PA5-18213 |
Price | |
Order / More Info | GRAF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |